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Cardiovascular Complications in Patients Hospitalized for COVID-19: A Cohort Study in Havana, Cuba

Luis Mariano de la Torre Fonseca1, Robert Alarcón Cedeño2, Víctor Alfonso Jiménez Díaz3

  • 1Intensive Care Unit, Comandante Manuel Fajardo Clinical-Surgical University Hospital, Habana, Cuba.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|February 23, 2023
PubMed

Insights

Older age and a history of ischemic heart disease are key predictors of cardiovascular complications in patients hospitalized with severe COVID-19, impacting survival rates.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • COVID-19 (Coronavirus Disease 2019) is associated with significant cardiovascular complications during hospitalization.
  • The specific risk factors for these complications remain incompletely understood.
  • Understanding these determinants is crucial for improving patient outcomes.

Purpose of the Study:

  • To investigate the relationship between in-hospital cardiovascular complications and patients' pre-existing cardiovascular history.
  • To identify predictors of cardiovascular complications in patients admitted to the Intensive Care Unit (ICU) with SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection.

Main Methods:

  • A prospective cohort study was conducted.
  • 373 patients diagnosed with SARS-CoV-2 and admitted to the ICU between March and October 2021 were included.
  • Data on cardiovascular history and hospital outcomes were collected.

Main Results:

  • 29.2% of patients experienced cardiovascular complications, including electrical disturbances (21.2%), acute coronary syndrome (5.9%), and pulmonary thromboembolism (1.9%).
  • Advanced age (Risk Ratio [RR]: 1.02) and a history of ischemic heart disease (RR: 2.23) were identified as independent predictors.
  • These predictors were significantly associated with increased risk of complications.

Conclusions:

  • Age and a history of ischemic heart disease are independent predictors of cardiovascular complications in severe COVID-19 patients.
  • These factors are significantly associated with poorer survival outcomes.
  • Further research is needed to elucidate the full spectrum of cardiovascular risk in COVID-19.
Abstract

Keywords:
Acute coronary syndromeCOVID-19Cardiac arrhythmiasCardiovascular complicationMortality

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