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Updated: Aug 9, 2025
Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Reemergence of Lymphocytic Choriomeningitis Mammarenavirus, Germany
Abstract:
Lymphocytic choriomeningitis mammarenavirus (LCMV) is a globally distributed zoonotic pathogen transmitted by house mice (Mus musculus). We report the reemergence of LCMV (lineages I and II) in wild house mice (Mus musculus domesticus) and LCMV lineage I in a diseased golden lion tamarin (Leontopithecus rosalia) from a zoo in Germany.
Insights
Lymphocytic choriomeningitis mammarenavirus (LCMV) has reemerged in Germany. This zoonotic virus was detected in wild house mice and a golden lion tamarin, highlighting potential risks in both wild and captive environments.
Area of Science:
- Veterinary Medicine
- Infectious Diseases
- Zoonotic Pathogens
Background:
- Lymphocytic choriomeningitis mammarenavirus (LCMV) is a significant zoonotic pathogen with global distribution.
- House mice (Mus musculus) are the primary reservoir and transmission vector for LCMV.
- LCMV poses risks to both animal and human health.
Purpose of the Study:
- To report the reemergence of LCMV in Germany.
- To identify LCMV lineages circulating in wild house mouse populations.
- To investigate LCMV infection in a diseased golden lion tamarin.
Main Methods:
- Surveillance of wild house mice (Mus musculus domesticus) for LCMV.
- Molecular detection and lineage determination of LCMV.
- Diagnostic investigation of a diseased golden lion tamarin (Leontopithecus rosalia).
Main Results:
- LCMV lineages I and II were detected in wild house mice.
- LCMV lineage I was identified in a diseased golden lion tamarin from a German zoo.
- This indicates a reemergence and spread of LCMV in Germany.
Conclusions:
- The findings confirm the reemergence of LCMV in Germany.
- LCMV poses a continued threat in both wild rodent populations and zoological collections.
- Ongoing monitoring is crucial for managing LCMV transmission risks.
