Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rolling Without Slipping01:09

Rolling Without Slipping

4.1K
People have observed the rolling motion without slipping ever since the invention of the wheel. For example, one can look at the interaction between a car's tires and the surface of the road. If the driver presses the accelerator to the floor so that the tires spin without the car moving forward, there must be kinetic friction between the wheels and the road's surface. If the driver slowly presses the accelerator, causing the car to move forward, the tires roll without slipping. It is...
4.1K
Rolling With Slipping01:14

Rolling With Slipping

5.5K
Rolling with slipping is a physical phenomenon that occurs when a rolling object experiences both rotational and linear motion but also experiences frictional forces that cause slipping. This phenomenon can occur in various situations, such as when a tire rolls on a wet road or a ball rolls on a rough surface.
An object's rolling motion is characterized by its rotation around its axis, while linear motion refers to the object's translational motion along a surface. Frictional forces can...
5.5K
Stokes' Law01:20

Stokes' Law

1.5K
Viscous forces, like friction, are intermolecular forces that resist the relative motion of molecules over each other. When a solid body moves through a liquid, viscous forces drag it in the opposite direction. The force's magnitude depends on the solid's shape and size, as well as its speed and the liquid's coefficient of viscosity, density and temperature.
The expression for the force on a solid spherical object in a fluid is called Stokes' law. Stokes' law is valid only...
1.5K
Pinching-off of Coated Vesicles01:32

Pinching-off of Coated Vesicles

3.2K
Vesicle budding is orchestrated by distinct cytosolic proteins such as adaptor proteins, coat proteins, and GTPases. To initiate vesicle budding, membrane-bending proteins containing crescent-shaped BAR domains bind to the lipid heads in the bilayer and distort the membrane to form a protein-coated vesicle bud. Adaptors proteins such as AP2 for clathrin-coated vesicles can nucleate on the deformed membrane. Finally, coat proteins such as clathrin or COPI and COPII assemble into a coat forming...
3.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dual role of the receptor kinase FERONIA in regulating tissue mechanics and growth.

Science advances·2026
Same author

Flow induced by bistable dynamics of soft magnetic pillars near a magnetoelastic instability.

Soft matter·2026
Same author

3D killing assay of cancer spheroids by cytotoxic T lymphocytes in anchored microfluidic droplets.

Methods in cell biology·2026
Same author

Controlling the Collective Transport of Large Passive Particles With Suspensions of Microorganisms.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Cytoplasmic flow induced by a rotating wire in living cells: magnetic rotational spectroscopy and finite element simulations.

Journal of the Royal Society, Interface·2026
Same author

SPEF1 mediates assembly of the central pair microtubule complexes in cilia of <i>Tetrahymena</i>.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: Aug 9, 2025

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

8.8K

Clogging of a Rectangular Slit by a Spherical Soft Particle.

Charles Paul Moore1,2, Julien Husson2, Arezki Boudaoud2

  • 1Institut Pasteur, Université Paris Cité, Physical microfluidics and Bioengineering, 25-28 Rue du Dr Roux, 75015 Paris, France.

Physical Review Letters
|February 24, 2023
PubMed
Summary

A soft particle trapped in a slit shows unusual flow behavior. Particle deformation dramatically increases flow resistance, leading to distinct flow and elastic-dominated regimes.

More Related Videos

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations
06:51

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

7.1K
Experimental Measurement of Settling Velocity of Spherical Particles in Unconfined and Confined Surfactant-based Shear Thinning Viscoelastic Fluids
10:28

Experimental Measurement of Settling Velocity of Spherical Particles in Unconfined and Confined Surfactant-based Shear Thinning Viscoelastic Fluids

Published on: January 3, 2014

13.7K

Related Experiment Videos

Last Updated: Aug 9, 2025

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions
11:51

Visually Based Characterization of the Incipient Particle Motion in Regular Substrates: From Laminar to Turbulent Conditions

Published on: February 22, 2018

8.8K
Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations
06:51

Microparticle Manipulation by Standing Surface Acoustic Waves with Dual-frequency Excitations

Published on: August 21, 2018

7.1K
Experimental Measurement of Settling Velocity of Spherical Particles in Unconfined and Confined Surfactant-based Shear Thinning Viscoelastic Fluids
10:28

Experimental Measurement of Settling Velocity of Spherical Particles in Unconfined and Confined Surfactant-based Shear Thinning Viscoelastic Fluids

Published on: January 3, 2014

13.7K

Area of Science:

  • Fluid dynamics
  • Soft matter physics
  • Microfluidics

Background:

  • Understanding particle behavior in confined geometries is crucial for microfluidic applications.
  • Soft particle deformation under flow can significantly alter fluid transport.

Purpose of the Study:

  • To investigate the pressure-flow rate relationship of a soft spherical particle in a rectangular slit.
  • To elucidate the underlying mechanisms of flow-induced particle deformation and its impact on fluid resistance.

Main Methods:

  • Numerical simulations were employed to model the interaction between a soft particle and fluid flow.
  • Low Reynolds number conditions were maintained to focus on viscous effects.

Main Results:

  • A nonmonotonic pressure-flow rate relation was observed.
  • Flow-induced particle deformation concentrated streamlines and pressure drop, increasing flow resistance by orders of magnitude.
  • Two distinct regimes were identified: flow-dominated and elastic-dominated.

Conclusions:

  • Soft particle deformation in slits creates complex flow dynamics.
  • The transition between flow-dominated and elastic-dominated regimes offers insights into controlling microfluidic transport.