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Updated: Aug 9, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Clinical and cost implications of deferred testing in low-risk patients with stable chest pain: a simulation using
Michael G Nanna1, Eric Yow2, Sreekanth Vemulapalli2
1Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT.
Abstract:
Current guidelines recommend a deferred testing approach in low-risk patients presenting with stable chest pain. After simulating a deferred testing approach using the PROMISE Minimal Risk Score to identify 915 minimal risk participants with cost data from the PROMISE trial, a deferred testing strategy was associated with an adjusted cost savings of -$748.74 (95% CI: -1646.97, 158.06) per participant and 74.6% of samples had better clinical outcomes and lower mean cost. This supports the current guideline recommended deferred testing approach in low-risk patients with stable chest pain.
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