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Long-term interplay between COVID-19 and chronic kidney disease
Helmut Schiffl1, Susanne M Lang2
1Universitätsklinikum LMU München, Medizinische Klinik IV, München, Germany. h-schiffl@t-online.de.
International Urology and Nephrology
|February 24, 2023
Summary
COVID-19 survivors face increased risks of long-term kidney damage, potentially leading to chronic kidney disease. Close monitoring of kidney function is crucial in post-acute care for these patients.
Area of Science:
- Nephrology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic's long-term effects on kidney function are under investigation.
- Understanding the relationship between COVID-19 and kidney disease is critical for survivor care.
Purpose of the Study:
- To review and summarize current data on the impact of COVID-19 on long-term kidney function.
- To clarify the clinical relevance of COVID-19-related kidney outcomes.
Main Methods:
- Systematic review of published literature.
- Synthesis of data on the bidirectional relationship between chronic kidney disease and COVID-19.
Main Results:
- A bidirectional link exists between chronic kidney disease (CKD) and COVID-19.
- CKD increases susceptibility to severe COVID-19 and mortality.
- COVID-19 survivors have a higher risk of adverse kidney outcomes, including new-onset CKD, independent of acute kidney injury (AKI).
- Risk of renal dysfunction post-COVID-19 correlates with infection severity.
Conclusions:
- Post-acute COVID-19 care necessitates vigilant monitoring of kidney function.
- Further large-scale prospective studies with extended follow-up are required.
- Future research should incorporate novel biomarkers, urinalysis, and biopsy data to fully assess kidney health post-COVID-19.
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