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Simple febrile seizures: new cut off for the duration of the crises

Raffaele Falsaperla1,2, Silvia Marino3, Giovanna Vitaliti1

  • 1Pediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.

Acta Neurologica Belgica
|February 24, 2023
PubMed

Insights

A new 6-minute cut-off for simple febrile seizures (SFS) in children indicates a higher risk of neurological issues and recurrence. This finding suggests revising the standard definition for better prognosis identification.

Area of Science:

  • Pediatric Neurology
  • Epileptology

Background:

  • The standard definition of simple febrile seizures (SFS) uses a 15-minute duration, potentially misclassifying some events.
  • A revised cut-off is needed to better identify SFS with a good prognosis.

Purpose of the Study:

  • To identify a new, more accurate duration cut-off for simple febrile seizures (SFS).
  • To differentiate SFS with benign prognoses from those with potential complications.

Main Methods:

  • Retrospective observational study of children with SFS from January to December 2018.
  • Analysis of EEG results, 12-month neurological follow-up, and seizure recurrence.
  • Identification of an optimal SFS duration cut-off at 6 minutes.

Main Results:

  • Febrile seizures (FS) exceeding 6 minutes were associated with EEG alterations.
  • Children with FS longer than 6 minutes showed increased neurological disorders.
  • A higher recurrence rate of FS was observed in the group with seizures lasting over 6 minutes.

Conclusions:

  • A 6-minute duration cut-off for febrile seizures (FS) better predicts potential complications.
  • Introducing a revised duration threshold can more accurately reflect the benign nature of simple febrile events.
  • This revised cut-off aids in better risk stratification for pediatric febrile seizures.
Abstract

Keywords:
ClassificationPediatricsRetrospective studySeizuresSimple febrile seizures

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