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Updated: Aug 9, 2025
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Agreement between a new optical low coherence reflectometry biometer and an anterior segment optical coherence
Yiran Wang1,2, Ting Wan2, Luze Liu2
1Eye Institute and Department of Ophthalmology, Institute for Medical and Engineering Innovation, Eye & ENT Hospital, Fudan University; NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, No.19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
Background:
To assess agreement of measurements between a new optical low coherence reflectometry (OLCR) biometer (SW-9000, Suoer, Tianjin, China) and a spectral-domain optical coherence tomographer (SD-OCT)/Placido topographer (MS-39, CSO, Florence, Italy) in healthy subjects.
Methods:
A total of 66 right eyes from 66 healthy subjects were enrolled in this prospective study. Three consecutive measurements were randomly obtained with both devices by the same experienced operator to assess agreement. Bland-Altman plots and 95% limits of agreement (LoA) were used to verify the agreement between the devices. Results are presented as mean ± standard deviation (SD).
Results:
The SD-OCT/Placido tomographer showed high agreement with the OLCR biometer for all parameters included in this study. The mean differences of central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth (AQD), mean keratometry (Km) and corneal diameter (CD) were 2.21 ± 2.67 μm (P < 0.001), - 0.10 ± 0.03 mm (P < 0.001), - 0.10 ± 0.04 mm (P < 0.001), - 0.01 ± 0.22 D (P = 0.773) and 0.20 ± 0.16 mm (P < 0.001), respectively. This implies that the inter-device difference in Km was not statistically significant, while the differences in CCT, ACD, AQD, CD were statistically but not clinically significant. The 95% LoAs of CCT, ACD, AQD, Km and CD were - 3.01 to 7.44 μm, - 0.16 to - 0.05 mm, - 0.18 to - 0.03 mm, - 0.45 to 0.43 D, and - 0.12 to 0.51 mm, respectively.
Conclusions:
For CCT, ACD, AQD, Km, and CD in healthy subjects, the new OLCR biometer has high agreement with the SD-OCT/Placido tomographer and can be used interchangeably due to the narrow range of 95% LoAs.
