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Updated: Aug 9, 2025

Generation and Expansion of Human Cardiomyocytes from Patient Peripheral Blood Mononuclear Cells
Published on: February 12, 2021
The Exciting Realities and Possibilities of iPS-Derived Cardiomyocytes
Fuga Takahashi1, Praneel Patel1, Takahiro Kitsuka1
1Department of Clinical Biomaterial Applied Science, Faculty of Medicine, University of Toyama, Toyama 930-8555, Japan.
Abstract:
Induced pluripotent stem cells (iPSCs) have become a prevalent topic after their discovery, advertised as an ethical alternative to embryonic stem cells (ESCs). Due to their ability to differentiate into several kinds of cells, including cardiomyocytes, researchers quickly realized the potential for differentiated cardiomyocytes to be used in the treatment of heart failure, a research area with few alternatives. This paper discusses the differentiation process for human iPSC-derived cardiomyocytes and the possible applications of said cells while answering some questions regarding ethical issues.
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