Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reliability of magnetoencephalography beta desynchronization for language lateralization in a subsequent memory effect paradigm.

Clinical neurophysiology practice·2026
Same author

Bubble-test for detection of a patent foramen ovale in young to middle-aged ischemic stroke patients.

Frontiers in neurology·2026
Same author

Long-term endocrine trajectories and reoperation risk after surgery for Rathke's cleft cysts: a single-center cohort study of 177 patients.

Pituitary·2026
Same author

BrainInsights: a comprehensive framework for pre-processing, analysis, and interpretation of neuroimaging data using traditional statistics and machine learning.

Frontiers in neuroinformatics·2026
Same author

Hospital resource use and costs in autoimmune encephalitis: a single-center retrospective cohort study.

Neurological research and practice·2026
Same author

Prediction, syntax and semantic grounding in the brain and large language models.

Scientific reports·2026
Same journal

Precision Proteomic Profiling of Systemic Lupus Erythematosus-Correlating Disease Activity and Complement Levels with Clinical Phenotypes.

Biomedicines·2026
Same journal

The Role of Salivary Microbiota in Pancreatic Cancer: From Screening to Tumor Progression and Treatment Response.

Biomedicines·2026
Same journal

Diagnostic Utility of Surface Electromyography for Identifying Muscles Affected by Myofascial Trigger Points: A Scoping Review.

Biomedicines·2026
Same journal

Performance Assessment of a Locally Semi-Automated NGS-Based Workflow for Homologous Recombination Deficiency Testing in High-Grade Serous Ovarian Carcinoma.

Biomedicines·2026
Same journal

Coupling and Uncoupling Pleiotropy Between Hypertension and Type 2 Diabetes Contribute to Exploring Potential Heterogeneity in Cardiovascular Risk in East Asian Population.

Biomedicines·2026
Same journal

Maternal Response to Therapeutic Plasma Exchange in Early Gestation: A Case Series of Thrombotic Microangiopathies and Neurological Disorders.

Biomedicines·2026
See all related articles

Related Experiment Video

Updated: Aug 9, 2025

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
09:33

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging

Published on: November 15, 2024

1.3K

MEG Node Degree for Focus Localization: Comparison with Invasive EEG.

Stefan Rampp1,2, Martin Kaltenhäuser1, Nadia Müller-Voggel1

  • 1Department of Neurosurgery, University Hospital Erlangen, 91054 Erlangen, Germany.

Biomedicines
|February 25, 2023
PubMed
Summary
This summary is machine-generated.

Resting state magnetoencephalography (MEG) reveals significant alterations in functional connectivity, specifically node degree (ND), within the seizure onset zone (SOZ). This finding suggests MEG-based ND could improve presurgical localization for epilepsy surgery.

Keywords:
MEGconnectivityepilepsyepilepsy surgeryfocus localizationgraph theory

More Related Videos

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

11.2K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

293

Related Experiment Videos

Last Updated: Aug 9, 2025

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging
09:33

Neuronavigated Focalized Transcranial Direct Current Stimulation Administered During Functional Magnetic Resonance Imaging

Published on: November 15, 2024

1.3K
A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
08:23

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy

Published on: November 13, 2016

11.2K
Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents
07:52

Multiscale Investigations of Cortical Processing by Integrating Laminar Polytrodes and Optogenetics with Micro Electrocorticography in Rodents

Published on: May 23, 2025

293

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Graph Theory

Background:

  • Epilepsy surgery is a key treatment for drug-resistant focal epilepsies.
  • Accurate localization of the epileptogenic zone is crucial for successful surgical outcomes.
  • Resting-state magnetoencephalography (MEG) may offer subtle insights into functional brain alterations relevant to epilepsy.

Purpose of the Study:

  • To investigate the relationship between node degree (ND), a graph-theoretical measure of functional connectivity, and the seizure onset zone (SOZ) in patients with focal epilepsy.
  • To assess the potential of resting-state MEG-derived ND as a tool for presurgical localization.

Main Methods:

  • Analyzed resting-state MEG data from 50 adult epilepsy patients using whole-brain, all-to-all connectivity analysis (imaginary part of coherence).
  • Calculated parcellated node degree (ND) and maximal node degree (mND) across different frequency bands.
  • Correlated ND with seizure onset zone (SOZ) localization on both lobar and sublobar levels, validated against invasive EEG (iEEG).

Main Results:

  • Significantly higher maximal node degree (mND) was observed within the SOZ compared to outside in lobar analyses for delta, theta, beta, and gamma bands (p < 0.05).
  • Sublobar analyses showed higher mND within the SOZ across delta, theta, and beta bands (p < 0.05).
  • Area under the curve (AUC) values ranged from 0.67-0.78 for lobar and 0.58-0.78 for sublobar analyses, indicating moderate discriminative power.

Conclusions:

  • Resting-state MEG-derived node degree (ND) is significantly associated with the seizure onset zone (SOZ) in delta, theta, and beta frequency bands.
  • ND analysis shows potential as an adjunctive tool for improving the localization accuracy in presurgical evaluation for epilepsy surgery.
  • Further research into MEG-based connectivity measures could enhance presurgical planning and patient outcomes.