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Acute Acalculous Cholecystitis Associated with Abscesses-An Unknown Dual Pathology.
Cristina Gluhovschi1,2, Florica Gadalean1,2, Silvia Velciov1,2
1Department of Internal Medicine II, Division of Nephrology, "Victor Babeș" University of Medicine and Pharmacy, County Emergency Hospital Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timișoara, Romania.
Biomedicines
|February 25, 2023
Summary
Renal abscesses can lead to acute acalculous cholecystitis (AAC) due to germ dissemination. Early gallbladder examination in renal abscess patients is crucial for timely intervention and favorable outcomes.
Area of Science:
- Urology
- Gastroenterology
- Infectious Diseases
Background:
- The relationship between renal and gallbladder pathology is poorly understood.
- Renal abscesses may disseminate to nearby organs like the gallbladder.
- Bile's environment can promote bacterial growth, leading to acute cholecystitis, even without gallstones (acute acalculous cholecystitis).
Purpose of the Study:
- To investigate the association between renal abscesses and acute acalculous cholecystitis (AAC).
Main Methods:
- A retrospective cohort study of 67 patients with renal abscesses.
- Abdominal ultrasound, complete blood count, liver function tests, serum creatinine, blood, and urine cultures were performed.
- Patients' demographics and clinical data were analyzed.
Main Results:
- Eight patients (11.94%) with renal abscesses also had acute cholecystitis (4 AAC, 4 calculous).
- All four AAC cases presented with sepsis; one had septic shock.
- No significant renal or hepatic impairment was noted in AAC patients; all cases resolved with antibiotics.
Conclusions:
- Acute acalculous cholecystitis (AAC) associated with renal abscesses may result from germ dissemination.
- Prompt clinical, laboratory, and imaging evaluation of the gallbladder is recommended for patients with renal abscesses.
- Early intervention improves outcomes for associated AAC.
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