Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mesenchymal Stem Cells

Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Feasibility of Patient-Derived 3D Gastrointestinal Stromal Tumour Models as Alternatives for In Vivo Mouse Models.

International journal of molecular sciences·2025

Same author

Alemtuzumab Exposure and T Lymphocyte Depletion: A Population Pharmacokinetic-Pharmacodynamic Model of Alemtuzumab Induction Therapy for Kidney Transplantation.

Clinical pharmacology and therapeutics·2025

Same author

Erythropoietin delivery through kidney organoids engineered with an episomal DNA vector.

Stem cell research & therapy·2025

Same author

Limited Risk of Microbial Contamination During Hypothermic and Normothermic Machine Perfusion of Donor Kidneys.

Transplant infectious disease : an official journal of the Transplantation Society·2025

Same author

Long-term Double-J stenting is superior to short-term Single-J stenting in kidney transplantation.

PloS one·2025

Same author

Multicenter, Real-World Clinical Evaluation of Alemtuzumab and Anti-Thymocyte Globulin for Severe Acute T Cell-Mediated Kidney Transplant Rejection.

Clinical transplantation·2024

Search research articles

Related Experiment Video

Updated: Aug 9, 2025

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications

Published on: December 8, 2016

Mesenchymal Stromal Cell-Based Therapy.

Dina Mönch^1,2, Marlies E J Reinders³, Martin J Hoogduijn³

¹Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.

|February 25, 2023

Summary

This summary is machine-generated.

Mesenchymal stromal cells (MSCs) show promise in clinical applications for bone repair and treating immune and transplant-related diseases. Further research is exploring their therapeutic potential across diverse medical fields.

More Related Videos

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Published on: October 31, 2012

Author Spotlight: Advancements in iPSCs and Genetic Disease Research

Author Spotlight: Advancements in iPSCs and Genetic Disease Research

Published on: October 20, 2023

Related Experiment Videos

Last Updated: Aug 9, 2025

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications

Published on: December 8, 2016

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate

Published on: October 31, 2012

Author Spotlight: Advancements in iPSCs and Genetic Disease Research

Author Spotlight: Advancements in iPSCs and Genetic Disease Research

Published on: October 20, 2023

Area of Science:

Regenerative Medicine
Cell Therapy
Immunomodulation

Background:

Mesenchymal stromal cells (MSCs) are extensively researched for clinical applications.
Investigated areas include bone repair, hematological and autoimmune diseases, and solid organ transplantation.

Discussion:

The broad therapeutic potential of MSCs is being explored.
Clinical applications span regenerative medicine and immunomodulation.

Key Insights:

MSCs demonstrate versatility in treating various conditions.
Their immunomodulatory properties are crucial for autoimmune and transplant therapies.

Outlook:

Ongoing research aims to optimize MSC-based therapies.
Future applications may include a wider range of diseases and injuries.