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Potential Pathophysiological Pathways in the Complex Relationships between OSA and Cancer.

Manuel Sánchez-de-la-Torre1,2, Carolina Cubillos2,3, Olivia J Veatch4

  • 1Group of Precision Medicine in Chronic Diseases, Respiratory Department, University Hospital Arnau de Vilanova and Santa María, Department of Nursing and Physiotherapy, Faculty of Nursing and Physiotherapy, IRBLleida, University of Lleida, 25003 Lleida, Spain.

Cancers
|February 25, 2023
PubMed
Summary

Obstructive sleep apnea (OSA) is linked to increased cancer risk and severity. Intermittent hypoxia in OSA activates pathways like HIF-1α, affecting cell functions and the microbiome, potentially driving cancer development.

Keywords:
biomarkercancerexosomesimmune systemintermittent hypoxiamalignancymicrobiomeobstructive sleep apneatumor

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