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Non-Convulsive Status Epilepticus in Aneurysmal Subarachnoid Hemorrhage: A Prognostic Parameter
Martin Vychopen1, Tim Lampmann2, Harun Asoglu2
1Department of Neurosurgery, University Hospital Leipzig, 04103 Leipzig, Germany.
Brain Sciences
|February 25, 2023
Summary
Non-convulsive status epilepticus (ncSE) is a rare but serious complication in subarachnoid hemorrhage (SAH) patients. ncSE is linked to poor prognosis and unfavorable outcomes, even with successful treatment.
Area of Science:
- Neurology
- Neurocritical Care
- Epileptology
Background:
- Non-convulsive status epilepticus (ncSE) is a critical complication in neurointensive care.
- ncSE in aneurysmal subarachnoid hemorrhage (SAH) patients is understudied.
- Investigating ncSE frequency and impact in SAH is crucial for patient outcomes.
Purpose of the Study:
- To determine the incidence of ncSE in aneurysmal SAH patients.
- To evaluate the influence of ncSE on patient outcomes.
- To identify predictors of unfavorable outcomes in SAH patients.
Main Methods:
- Retrospective analysis of SAH patients undergoing EEG monitoring.
- Evaluation of clinical, radiological, and demographic data.
- Outcome assessment using the modified Rankin Scale (mRS) at 6 months.
Main Results:
- ncSE was diagnosed in 3.7% of 171 SAH patients.
- Only one patient with ncSE achieved a favorable outcome.
- Independent predictors of unfavorable outcome included ncSE, poor-grade SAH, age, and DIND.
Conclusions:
- ncSE development in SAH patients correlates with poor prognosis.
- ncSE is a significant predictor of unfavorable outcomes.
- Long-term outcomes remain poor in SAH patients with ncSE, irrespective of treatment success.
