Using Nanomaterials as Excellent Immobilisation Layer for Biosensor Design

Area of Science:

• Biomedical Engineering
• Materials Science
• Nanotechnology

Background:

• Nanotechnology advancements offer new possibilities for device fabrication, particularly in biosensor design for biomedical applications.
• Nanomaterials possess advantageous properties such as biocompatibility, conductivity, large surface area, and catalytic activity, making them ideal for biosensor development.
• The review focuses on the use of nanomaterials as immobilization candidates for high-impact biosensors.

Purpose of the Study:

• To review the efficient utilization of nanomaterials in biosensor fabrication.
• To explore various nanomaterials including carbon-based forms (graphene, carbon nanotubes, nanoparticles, nanodots) and MXenes.
• To discuss the synergistic effects of combining these nanomaterials with metal oxides.

Main Methods:

• Literature review of nanomaterial applications in biosensor design.
• Analysis of synthesis origins, challenges, and chemical incorporation strategies for nanomaterials.
• Examination of the synergistic impact of nanomaterial combinations, particularly with metal oxides.

Main Results:

• Nanomaterials are effective immobilization candidates for biosensors owing to their excellent properties.
• Carbon nanomaterials (graphene derivatives, CNTs, nanoparticles, nanodots) and MXenes show significant promise.
• Synergistic effects are observed when nanomaterials are combined with metal oxides, enhancing biosensor performance.

Conclusions:

• Nanomaterials are crucial for developing advanced biosensors with improved sensitivity and specificity.
• The integration of diverse nanomaterials, including carbon-based forms and MXenes, offers versatile platforms for biosensing.
• Future prospects lie in optimizing the synthesis and application of these nanomaterials for next-generation biomedical devices.