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Molecularly Imprinted Polymer-Based Luminescent Chemosensors
1Department of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong 518057, China.
Biosensors
|February 25, 2023
Summary
Molecularly imprinted polymer (MIP)-based luminescent chemosensors offer sensitive and specific detection. This review covers their design, sensing strategies, and applications in various fields.
Area of Science:
- Analytical Chemistry
- Materials Science
- Nanotechnology
Background:
- Molecularly imprinted polymers (MIPs) offer high specificity in molecular recognition.
- Luminescence detection provides high sensitivity for analyte quantification.
- Combining MIPs with luminescence creates powerful chemosensors.
Purpose of the Study:
- To review the design strategies for luminescent MIP-based chemosensors.
- To discuss various sensing approaches and applications.
- To explore future prospects and limitations of these sensors.
Main Methods:
- Incorporation of luminescent functional monomers into MIPs.
- Physical entrapment of luminescent materials within MIPs.
- Covalent attachment of signaling elements onto MIPs.
- Surface-imprinting polymerization on luminescent nanomaterials.
Main Results:
- Luminescent MIPs demonstrate effective molecular recognition and sensitive detection.
- Various construction strategies yield versatile chemosensors.
- Applications span biosensing, bioimaging, food safety, and clinical diagnosis.
Conclusions:
- Luminescent MIP chemosensors are highly promising for diverse analytical challenges.
- Further development is needed to overcome current limitations.
- Future research will focus on enhancing performance and expanding applications.
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