Related Experiment Video For X-ray image
Updated: Aug 9, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Published on: August 16, 2020
DTBV: A Deep Transfer-Based Bone Cancer Diagnosis System Using VGG16 Feature Extraction
G Suganeshwari1, R Balakumar2, Kalimuthu Karuppanan3
1School of Computer Science and Engineering, Chennai Campus, Vellore Institute of Technology, Chennai 600127, India.
Abstract:
Among the many different types of cancer, bone cancer is the most lethal and least prevalent. More cases are reported each year. Early diagnosis of bone cancer is crucial since it helps limit the spread of malignant cells and reduce mortality. The manual method of detection of bone cancer is cumbersome and requires specialized knowledge. A deep transfer-based bone cancer diagnosis (DTBV) system using VGG16 feature extraction is proposed to address these issues. The proposed DTBV system uses a transfer learning (TL) approach in which a pre-trained convolutional neural network (CNN) model is used to extract features from the pre-processed input image and a support vector machine (SVM) model is used to train using these features to distinguish between cancerous and healthy bone. The CNN is applied to the image datasets as it provides better image recognition with high accuracy when the layers in neural network feature extraction increase. In the proposed DTBV system, the VGG16 model extracts the features from the input X-ray image. A mutual information statistic that measures the dependency between the different features is then used to select the best features. This is the first time this method has been used for detecting bone cancer. Once selected features are selected, they are fed into the SVM classifier. The SVM model classifies the given testing dataset into malignant and benign categories. A comprehensive performance evaluation has demonstrated that the proposed DTBV system is highly efficient in detecting bone cancer, with an accuracy of 93.9%, which is more accurate than other existing systems.
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