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Published on: May 22, 2018
Dependence of the Atrioventricular Conduction Time on the Conduction through the Atrioventricular Node and
Bartosz Żuchowski1, Krzysztof Błaszyk2, Jarosław Piskorski3
1Department of Cardiology Intensive Therapy, Poznan University of Medical Sciences, Przybyszewskiego 49, 60-355 Poznan, Poland.
Insights
Atrioventricular conduction time primarily depends on the atrioventricular node (AVN), not the His-Purkinje system (HPS). Men exhibit longer conduction times, but the relationships between these intervals are similar across sexes.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Conduction System
Background:
- The cardiac conduction system regulates heart depolarization.
- Atrioventricular (AV) conduction time is influenced by the atrioventricular node (AVN) and His-Purkinje system (HPS).
Purpose of the Study:
- To investigate the relationship between AV conduction time (AV interval) and its components, the AH (AVN) and HV (HPS) intervals.
- To compare sex differences in these electrophysiological intervals and their associations.
Main Methods:
- Intracardiac electrophysiological recordings were obtained from 64 patients.
- AH, HV, and AV intervals were measured from resting tracings.
- Statistical analysis was performed to assess correlations and sex differences.
Main Results:
- Mean AH interval was 85.9 ms, HV 43.7 ms, and AV 129.6 ms.
- Men had significantly longer AH, HV, and AV intervals compared to women.
- AV intervals strongly correlated with AH intervals (r² = 0.65) but not HV intervals (r² = 0.05).
Conclusions:
- Atrioventricular conduction time is predominantly determined by AVN conduction.
- The His-Purkinje system has a lesser impact on overall AV conduction time.
- While men show longer conduction times, the underlying relationships between AVN, HPS, and total AV intervals are similar in both sexes.
Abstract:
The electrical depolarization of the heart passes through various structures of the cardiac conduction system, which modify its conduction to different extents. In this study, we investigated the relationship between the atrioventricular conduction time (AV interval) and its contributors, the atrioventricular node (AVN) and the His-Purkinje system (HPS), as represented by the AH and HV intervals, respectively. We also compared sex differences in these intervals and their relations. Resting intracardiac tracings lasting 5 min were obtained from 64 patients (33 women) during an invasive electrophysiological study. The aforementioned intervals were measured for all consecutive beats. The mean AH interval was 85.9 ms, HV 43.7 ms, and AV 129.6 ms. Men had longer AH (80.0 vs. 65.9 ms), HV (38.4 vs. 35.3 ms), and AV intervals (124.7 vs. 108.5 ms) than women. The AV intervals were linearly correlated with AH intervals in all patients (r2 = 0.65). No significant correlation was found between AV and HV intervals in all patients (r2 = 0.05). There were no sex differences in these associations. Our results suggest that the atrioventricular conduction time depends mainly on the conduction through the AVN and less on the HPS. These relations are similar in both sexes, although men had longer conduction times through the AVN, HPS, and total atrioventricular conduction time.
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