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Updated: Aug 9, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Catheter Ablation for Atrial Fibrillation in Structural Heart Disease: A Review
Francesco Maria Angelo Brasca1, Roberto Menè1,2, Giovanni Battista Perego1
1Department of Cardiovascular Neural and Metabolic Sciences, San Luca Hospital, IRCCS Istituto Auxologico Italiano, 20149 Milan, Italy.
Insights
Atrial fibrillation (AF) is a common arrhythmia, especially in patients with structural heart disease (SHD). Catheter ablation (CA) for AF may offer benefits beyond symptom relief in these patients.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Atrial fibrillation (AF) is the most common cardiac arrhythmia.
- Patients with structural heart disease (SHD) have a higher risk of AF and adverse hemodynamic consequences.
- Catheter ablation (CA) is a standard treatment for symptomatic AF.
Purpose of the Study:
- To review the current understanding of catheter ablation (CA) for atrial fibrillation (AF) in patients with structural heart disease (SHD).
- To explore potential benefits of CA beyond symptom management in this population.
Main Methods:
- Literature review of studies investigating catheter ablation for AF in patients with structural heart disease.
- Synthesis of evidence on the impact of CA on hemodynamic effects and clinical outcomes in SHD patients with AF.
Main Results:
- Catheter ablation is an established therapy for symptomatic relief in AF patients.
- Emerging evidence suggests CA may confer benefits beyond symptom control in patients with SHD.
- Further research is ongoing to fully elucidate these extended benefits.
Conclusions:
- Catheter ablation is a key therapeutic option for AF, particularly in patients with SHD.
- The role of CA in managing SHD patients with AF is expanding beyond symptom relief.
- This review consolidates current knowledge on CA's impact on SHD patients with AF.
Abstract:
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Patients with structural heart disease (SHD) are at an increased risk of developing this arrhythmia and are particularly susceptible to the deleterious hemodynamic effects it carries. In the last two decades, catheter ablation (CA) has emerged as a valuable strategy for rhythm control and is currently part of the standard care for symptomatic relief in patients with AF. Growing evidence suggests that CA of AF may have potential benefits that extend beyond symptoms. In this review, we summarize the current knowledge of this intervention on SHD patients.
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