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Proteomics

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...

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Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication

Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication

Published on: September 20, 2016

Food for Thought: Proteomics for Meat Safety.

Svetlana Tarbeeva¹, Anna Kozlova¹, Elizaveta Sarygina¹

¹Institute of Biomedical Chemistry, 119121 Moscow, Russia.

Life (Basel, Switzerland)

|February 25, 2023

Summary

Proteomics offers advanced insights into foodborne bacteria and their resistance mechanisms. This review highlights its benefits for food safety, complementing genomic methods for enhanced pathogen detection and analysis.

Keywords:

Listeria Pseudomonas Salmonella antibiotics bacteria food safety meat packing plant meat processing resistance

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Last Updated: Aug 9, 2025

Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication

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Area of Science:

Food safety
Microbiology
Proteomics

Background:

Bacterial contamination in food poses significant public health and economic risks.
Microbiome screening is crucial for ensuring food production safety and consumer health.
Proteomics provides a detailed view of protein functions, vital for understanding biological systems.

Purpose of the Study:

To review proteomics findings in food safety over the past decade.
To assess the impact of proteomics on pathogen detection and resistance analysis.
To highlight the advantages of integrating proteomics with other omics approaches.

Main Methods:

Analysis of over 48,000 scientific articles using the ScanBious web-based tool.
Review of proteomics applications for detecting foodborne pathogens.
Examination of proteomic methods for studying antibiotic and disinfectant resistance.

Main Results:

Proteomics enables sensitive, specific, and in-depth elucidation of bacterial interactions.
Bioinformatics algorithms aid in mapping proteomic data to genomic and transcriptomic information.
Proteomics significantly benefits the field of food safety by enhancing pathogen detection and resistance studies.

Conclusions:

Proteomics is a powerful tool for advancing food safety research.
Combining proteomics with genomics and metagenomics offers a comprehensive approach to food safety.
Mass spectrometry-based proteomics provides panoramic and targeted analyses for food production safety.