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Related Concept Videos

Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
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Pleura of the Lungs01:13

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
231
Pneumothorax-I01:26

Pneumothorax-I

280
A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
280
Pneumothorax-II01:27

Pneumothorax-II

243
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
243

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Correction: Yalçın et al. Impact of SGLT2 Inhibitors on Cardiovascular Risk Scores, Metabolic Parameters, and Laboratory Profiles in Type 2 Diabetes. <i>Life</i> 2025, <i>15</i>, 722.

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Updated: Aug 9, 2025

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
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Pleural Space Infections.

Sean P F Foley1, John Scott Parrish1

  • 1Department of Pulmonary, Critical Care and Sleep Medicine, Naval Medical Center San Diego, San Diego, CA 92134, USA.

Life (Basel, Switzerland)
|February 25, 2023
PubMed
Summary
This summary is machine-generated.

Pleural space infections, known for millennia, still cause significant global health issues. Recent advancements enhance understanding and treatment of these challenging infections.

Keywords:
empyemainterventional pulmonologyparapneumonic effusionpleural diseasepleural effusionpleural infectionspleural sepsispneumoniapulmonary infectionsunilateral pleural effusion

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Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Critical Care Medicine

Background:

  • Pleural space infections are historically significant and remain a major cause of worldwide morbidity and mortality.
  • Understanding of the pathophysiology and treatment options for these infections has evolved considerably.

Purpose of the Study:

  • To review recent advancements in the understanding of pleural space infections.
  • To provide updates on current and novel treatment strategies for patients with these infections.

Main Methods:

  • Comprehensive literature review of recent pertinent studies.
  • Synthesis of information on history, epidemiology, pathophysiology, diagnosis, and management.
  • Discussion of established and emerging treatment modalities.

Main Results:

  • Significant expansion in the collective understanding of causative pathophysiology.
  • Development of new and improved treatment options.
  • Identification of key areas for future research and clinical practice.

Conclusions:

  • Pleural space infections require ongoing research and clinical attention due to their persistent impact.
  • Updated knowledge and treatment modalities are crucial for improving patient outcomes.
  • This review synthesizes current literature to guide the management of these complex infections.