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Updated: Aug 8, 2025
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Airway and Respiratory Devices in the Prevention of Ventilator-Associated Pneumonia
Luis Coelho1,2,3, Patricia Moniz2, Gonçalo Guerreiro2
1NOVA Medical School, New University of Lisbon, 1300 Lisbon, Portugal.
Abstract:
Ventilator-associated pneumonia (VAP) is the most common ICU-acquired infection among patients under mechanical ventilation (MV). It may occur in up to 50% of mechanically ventilated patients and is associated with an increased duration of MV, antibiotic consumption, increased morbidity, and mortality. VAP prevention is a multifaceted priority of the intensive care team. The use of specialized artificial airways and other devices can have an impact on the prevention of VAP. However, these devices can also have adverse effects, and aspects of their efficacy in the prevention of VAP are still a matter of debate. This article provides a narrative review of how different airway and respiratory devices may help to reduce the incidence of VAP.
Insights
Ventilator-associated pneumonia (VAP) is a common ICU infection. This review examines how specialized airway and respiratory devices can help prevent VAP in mechanically ventilated patients.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Respiratory Therapy
Background:
- Ventilator-associated pneumonia (VAP) is the most frequent intensive care unit (ICU)-acquired infection.
- VAP affects up to 50% of mechanically ventilated patients, increasing mortality, morbidity, and healthcare costs.
Purpose of the Study:
- To review the role of specialized artificial airways and respiratory devices in VAP prevention.
- To discuss the efficacy and potential adverse effects of these devices in reducing VAP incidence.
Main Methods:
- This article presents a narrative review of existing literature.
- It synthesizes findings on various airway and respiratory adjuncts used for VAP prevention.
Main Results:
- Specialized devices show potential in reducing VAP rates.
- However, their effectiveness and safety profiles require ongoing evaluation and debate.
Conclusions:
- Optimizing the use of airway and respiratory devices is crucial for VAP prevention strategies.
- Further research is needed to clarify the definitive role and best practices for these devices in clinical settings.
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