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Paralytic poliomyelitis in vaccinated children
E Dussaix1, G Huault, P Landrieu
1Laboratoire de Virologie, Hôpital Bicêtre, Le Kremlin Bicêtre, France.
Neuropediatrics
|August 1, 1987
Summary
Two healthy children developed paralytic poliomyelitis despite receiving four inactivated poliovaccine (IPV) doses. Their normal immune systems failed to produce antibodies, suggesting IPV may lack sufficient antigenicity.
Area of Science:
- Immunology
- Vaccinology
- Infectious Diseases
Background:
- Paralytic poliomyelitis remains a public health concern.
- Inactivated poliovaccine (IPV) is a key tool for polio eradication.
- Vaccine response can vary among individuals.