Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radical Autoxidation01:20

Radical Autoxidation

2.2K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ALOX15 orchestrates mitochondrial antiviral immunity and serves as a host target for anti-influenza therapy.

Nature immunology·2026
Same author

A non-enzymatic sensor based on rGO/Pt NPs/Fc-Tyr/POPD nanocomposite for hydrogen peroxide determination in liver cancer tissues.

Mikrochimica acta·2026
Same author

Loofah Fiber-Reinforced Eutectogel for Motion-Robust and High-Fidelity Surface Electromyography.

ACS sensors·2026
Same author

Construction and prototype effect evaluation of a multi-agent collaborative system for operating room nursing.

Frontiers in digital health·2026
Same author

Unraveling stepwise pressure effects on interfacial structure and electrochemical dynamics in sulfide-based all-solid-state Lithium batteries.

Journal of colloid and interface science·2026
Same author

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Related Experiment Video

Updated: Aug 8, 2025

Evaluation of Oxidative Stress in Biological Samples Using the Thiobarbituric Acid Reactive Substances Assay
06:19

Evaluation of Oxidative Stress in Biological Samples Using the Thiobarbituric Acid Reactive Substances Assay

Published on: May 12, 2020

29.2K

Potential of Tamarind Shell Extract against Oxidative Stress In Vivo and In Vitro.

Weixi Li1, Rongping Huang1, Shaocong Han1

  • 1College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.

Molecules (Basel, Switzerland)
|February 25, 2023
PubMed
Summary

Tamarind shell extract (TSE) contains eight key flavonoids with potent antioxidant properties. This study confirms TSE

Keywords:
AAPHflavonoidsfree radicals scavengingoxidative stresstamarin shell extracttert-butyl hydroperoxidezebrafish

More Related Videos

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
08:16

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

8.8K
Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
07:40

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

1.2K

Related Experiment Videos

Last Updated: Aug 8, 2025

Evaluation of Oxidative Stress in Biological Samples Using the Thiobarbituric Acid Reactive Substances Assay
06:19

Evaluation of Oxidative Stress in Biological Samples Using the Thiobarbituric Acid Reactive Substances Assay

Published on: May 12, 2020

29.2K
Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro
08:16

Method for the Assessment of Effects of a Range of Wavelengths and Intensities of Red/near-infrared Light Therapy on Oxidative Stress In Vitro

Published on: March 21, 2015

8.8K
Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
07:40

Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy

Published on: May 26, 2023

1.2K

Area of Science:

  • Phytochemistry and Pharmacology
  • Natural Product Chemistry
  • Oxidative Stress Research

Background:

  • Tamarind shell is a rich source of bioactive flavonoids.
  • Flavonoids possess significant biological activities, including antioxidant potential.
  • Understanding tamarind shell's chemical composition is crucial for its utilization.

Purpose of the Study:

  • To analyze the chemical constituents of tamarind shell extract (TSE).
  • To evaluate the in vitro and in vivo antioxidant capacity of TSE.
  • To investigate the specific antioxidant contributions of identified flavonoids.

Main Methods:

  • Extraction of tamarind shells using 95% ethanol.
  • Chemical profiling of TSE using ultra-performance liquid chromatography-electrospray tandem mass spectrometry (UPLC-MS/MS).
  • In vitro antioxidant activity assessment via oxygen radical absorbance capacity (ORAC) assay.
  • In vivo antioxidant evaluation in cell (ATDC5) and zebrafish models exposed to oxidative stressors (AAPH and t-BHP).

Main Results:

  • Eight flavonoids were identified and quantified in TSE: (+)-catechin, taxifolin, myricetin, eriodictyol, luteolin, morin, apigenin, and naringenin.
  • TSE demonstrated strong free radical scavenging activity in vitro (ORAC assay).
  • TSE significantly reduced reactive oxygen species (ROS) and malondialdehyde (MDA) levels while restoring superoxide dismutase (SOD) activity in cellular and zebrafish models.

Conclusions:

  • Tamarind shell extract possesses significant in vitro and in vivo antioxidant potential, attributed to its rich flavonoid content.
  • The identified flavonoids contribute to the observed antioxidant effects, offering protection against oxidative damage.
  • This study provides a scientific basis for the development and application of tamarind shell as a source of natural antioxidants.