Chitosan-Based Nanoparticles as Effective Drug Delivery Systems-A review

Area of Science:

• Biomaterials Science
• Nanotechnology
• Pharmaceutical Sciences

Background:

• Chitosan-based nanoparticles (ChNPs) are increasingly recognized for their versatile applications.
• Their biocompatibility and biodegradability make them ideal candidates for drug delivery systems (DDS).
• Recent decades have seen significant research interest in ChNPs.

Purpose of the Study:

• To provide a comprehensive overview of ChNP preparation methods.
• To review the applications of ChNPs in medicine, particularly as nanocarriers.
• To discuss chitosan's properties relevant to drug delivery and NP production.

Main Methods:

• Literature review of ChNP preparation techniques.
• Analysis of ChNP applications in various medical fields.
• Classification of ChNP morphological features and drug attachment methods.

Main Results:

• ChNPs offer controlled release of encapsulated drugs and active compounds.
• Morphological characteristics influence ChNP application efficacy.
• Various administration routes, including oral, ocular, dermal, and transdermal, are explored.

Conclusions:

• Chitosan nanoparticles are highly promising for advanced drug delivery systems.
• Understanding ChNP properties and production is crucial for optimizing therapeutic outcomes.
• Further research into ChNP applications will advance targeted medicine.