Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions
Gemma Mestre-Bach1, Marc N Potenza2,3,4,5,6,7
1Facultad de Ciencias de la Salud, Universidad Internacional de La Rioja, 26006 Logroño, Spain.
Abstract:
The reward system is highly relevant to behavioral addictions such as gambling disorder (GD), internet gaming disorder (IGD), and food addiction/binge eating disorder (FA/BED). Among other brain regions, the ventral striatum (VS) has been implicated in reward processing. The main objective of the present state-of-the-art review was to explore in depth the specific role of the VS in GD, IGD and FA/BED, understanding it as a possible biomarker of these conditions. Studies analyzing brain changes following interventions for these disorders, and especially those that had explored possible treatment-related changes in VS, are discussed. More evidence is needed on how existing treatments (both pharmacological and psychobehavioral) for behavioral addictions affect the activation of the VS and related circuitry.
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