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Polymeric Systems for the Controlled Release of Flavonoids
Gianni Pecorini1, Elisabetta Ferraro2, Dario Puppi1
1BIOLab Research Group, Department of Chemistry and Industrial Chemistry, University of Pisa, UdR INSTM Pisa, Via Moruzzi 13, 56124 Pisa, Italy.
Pharmaceutics
|February 25, 2023
Summary
This review explores polymeric systems for controlled flavonoid release, enhancing their therapeutic potential in medicine. Encapsulating flavonoids in polymers improves drug delivery and efficacy for various biomedical applications.
Area of Science:
- Biomedical Science
- Polymer Science
- Pharmacology
Background:
- Flavonoids possess diverse biological properties, including anticancer, anti-inflammatory, and antidiabetic effects.
- Their therapeutic efficacy is limited by rapid clearance and low bioavailability.
- Polymeric systems offer a promising strategy for controlled flavonoid delivery.
Purpose of the Study:
- To provide an updated overview of polymeric systems for controlled flavonoid release.
- To describe different flavonoid classes and commonly used polymers for drug delivery.
- To review relevant literature on flavonoid-polymer systems for biomedical applications.
Main Methods:
- Literature review of scientific publications on flavonoid encapsulation and controlled release.
- Description of various flavonoid classes and their biological properties.
- Discussion of different polymeric systems, preparation techniques, and their applications.
Main Results:
- Various polymeric systems have been developed for controlled release of flavonoids.
- Different flavonoids, sourced from natural products, show significant biological activities.
- Polymer encapsulation enhances flavonoid bioavailability and therapeutic outcomes.
Conclusions:
- Polymeric systems are effective for controlled release of flavonoids, improving their therapeutic efficacy.
- Further research into flavonoid-polymer systems holds promise for novel drug delivery strategies.
- This review highlights key advancements and future directions in the field.
Keywords:
bioavailabilitybiomedical devicesdrug deliverynanoparticlesnatural polymersphytotherapeuticspolyphenolic compoundsscaffoldssynthetic polymersMore Related Videos
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