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Updated: Aug 8, 2025

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
Published on: January 9, 2015
Economic Analyses of Obsessive-Compulsive Disorder Interventions: A Systematic Review
Emily R Strouphauer1, Olivia J Morris1, Keaton J Soileau1
1Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, One Baylor Plaza, MS: 350, Houston, TX, 77030, USA.
Cost-effectiveness data for obsessive-compulsive disorder (OCD) treatments are limited. Internet-based CBT shows promise for economic practicality, but more research is needed to compare it with standard care.
Area of Science:
- Neuroscience
- Psychiatry
- Health Economics
Background:
- Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric condition.
- Effective treatments like CBT and SSRIs exist, but their cost-effectiveness needs evaluation.
- Understanding intervention costs is crucial for patient-centered care.
Approach:
- A systematic literature review was conducted.
- Studies were sourced from major databases (PubMed, Embase, Ovid MEDLINE, Cochrane).
- Cost-effectiveness studies published in English between 2010 and 2022 were included.
Key Points:
- 18 cost-effectiveness studies were reviewed.
- Internet-based CBT demonstrated cost-effectiveness for adults and children with OCD.
- Serotonin reuptake inhibitors showed cost utility over CBT in one study.
- High-intensity neuroaugmentation was evaluated for treatment-refractory OCD.
Conclusions:
- Cost-effectiveness data for OCD interventions remain scarce.
- Alternative therapies may offer economic practicality without compromising efficacy.
- Further research is needed to compare emerging treatments with standard CBT.
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