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Bioactive Compounds (BACs): A Novel Approach to Treat and Prevent Cardiovascular Diseases
Syed Riaz Ud Din1, Sumbul Saeed2, Shahid Ullah Khan3
1Department of Microbiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, P.R China.
Insights
Green-colored foods contain bioactive compounds (BACs) that show promise in preventing and treating cardiovascular diseases (CVDs). This review explores their health benefits, including anti-inflammatory and antioxidant effects, for better CVD management.
Area of Science:
- Nutritional Science
- Cardiology
- Pharmacology
Background:
- Cardiovascular diseases (CVDs) are a leading cause of death globally, resulting in significant economic burdens.
- Bioactive compounds (BACs) from foods offer nutritional benefits and therapeutic potential for various health conditions.
- Epidemiological studies highlight several BACs as promising candidates for CVD treatment and prevention.
Purpose of the Study:
- To review and synthesize existing data on green-colored foods and their BACs for CVD prevention, diagnosis, and treatment.
- To discuss the oral delivery, bioavailability, and physiological effects of vegetable and fruit-derived BACs.
- To elaborate on the specific health benefits of these BACs, including anti-inflammatory, antioxidant, and cardioprotective properties.
Main Methods:
- Comprehensive literature review of studies on green foods, their BACs, and cardiovascular health.
- Analysis of research on the oral bioavailability and physiological impacts of BACs from fruits and vegetables.
- Synthesis of data regarding the therapeutic characteristics of medicinal plants for CVD management.
Main Results:
- Green-colored foods and their BACs possess properties beneficial for cardiovascular health, such as anti-inflammatory, antioxidant, and blood pressure-lowering effects.
- Oral delivery of BACs from fruits and vegetables can be optimized, influencing their bioavailability and physiological impact.
- Medicinal plants rich in BACs demonstrate multifaceted applications in managing CVDs, including atherosclerosis and diabetes.
Conclusions:
- Green foods and their bioactive compounds represent a significant, underexplored resource for the prevention and treatment of cardiovascular diseases.
- Further research into the oral delivery and bioavailability of these compounds can enhance their therapeutic efficacy.
- This review opens new avenues for developing effective, natural-based strategies for better CVD prognosis and management.
Abstract:
Cardiovascular diseases (CVDs) are one of the leading disorders of serious death and cause huge economic loss to patients and society. It is estimated that about 18 million people have a high death ratio due to the incidence of CVDs such as (stroke, coronary heart disease, and non-ischemic heart failure). Bioactive compounds (BACs) are healthy nutritional ingredients providing beneficial effects and nutritional value to the human body. Epidemiological studies strongly shed light on several bioactive compounds that are favorable candidates for CVDs treatment. Globally, the high risk of CVDs and related results on human body parts made them a serious scenario in all communities. In this present review, we intend to collect previously published data concerned over the years concerning green-colored foods and their BACs that aim to work in the prevention, diagnosis, and/or systematic treating CVDs. We also comprehensively discussed the oral delivery of several bioactive compounds derived from fruits and vegetables and their bioavailability and physiological effects on human health. Moreover, their important characteristics, such as anti-inflammatory, lowering blood pressure, anti-obesity, antioxidant, anti-diabetics, lipid-lowering responses, improving atherosclerosis, and cardio protective properties, will be elaborated further. More precisely, medicinal plants' advantages and multifaceted applications have been reported in this literature to treat CVDs. To the best of our knowledge, this is our first attempt that will open a new window in the area of CVDs with the opportunity to achieve a better prognosis and effective treatment for CVDs.
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