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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Approach to nutritional rickets.

Hüseyin Anıl Korkmaz1, Raja Padidela2, Behzat Ozkan1

  • 1Department of Pediatrics, Division of Pediatric Endocrinology, Dr. Behçet Uz Pediatric Diseases and Surgery training and Research hospital, İzmir, Türkiye.

Journal of Pediatric Endocrinology & Metabolism : JPEM
|February 27, 2023
PubMed
Summary
This summary is machine-generated.

Nutritional rickets, caused by vitamin D or calcium deficiency, affects bone growth due to impaired chondrocyte apoptosis and mineralization. This review covers its causes, symptoms, diagnosis, and treatment.

Keywords:
nutritional ricketsricketsvitamin Dvitamin D deficiency

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Area of Science:

  • Pediatrics
  • Endocrinology
  • Nutritional Science

Background:

  • Rickets is a skeletal disease in growing children.
  • It involves impaired chondrocyte apoptosis and growth plate mineralization.
  • Nutritional deficiencies (vitamin D, calcium) are a primary cause.

Purpose of the Study:

  • To review the pathogenesis of nutritional rickets.
  • To outline clinical signs and diagnostic methods.
  • To discuss current management strategies.

Main Methods:

  • Literature review of nutritional rickets.
  • Synthesis of information on pathogenesis, clinical presentation, and management.

Main Results:

  • Nutritional rickets results from impaired apoptosis and mineralization.
  • Clinical signs vary depending on severity and duration.
  • Diagnosis involves clinical, biochemical, and radiological findings.

Conclusions:

  • Nutritional rickets is a significant global health issue.
  • Early diagnosis and appropriate management are crucial.
  • Addressing vitamin D and calcium deficiencies is key to prevention and treatment.