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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Leveraging diagnostic stewardship within antimicrobial stewardship programmes.

Kimberly C Claeys¹, Melissa D Johnson^2,3

¹University of Maryland School of Pharmacy, Department of Practice Science and Health Outcomes Research, Baltimore, MD, USA.

Drugs in Context

|February 27, 2023

Summary

This summary is machine-generated.

Diagnostic stewardship optimizes infectious disease testing to improve patient care and antimicrobial use. Antimicrobial stewardship programs must lead in developing these crucial diagnostic interventions.

Keywords:

antimicrobial stewardship diagnostic stewardship

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Area of Science:

Infectious Diseases
Clinical Microbiology
Healthcare Management

Background:

Diagnostic stewardship involves optimizing the ordering, processing, and reporting of diagnostic tests.
It complements traditional antimicrobial stewardship efforts by ensuring appropriate test utilization.
Growing attention on diagnostic stewardship necessitates integration with antimicrobial stewardship programs.

Purpose of the Study:

To review the necessity of diagnostic and antimicrobial stewardship.
To explore the synergistic relationship between diagnostic and antimicrobial stewardship.
To highlight the benefits of diagnostic stewardship for antimicrobial stewardship programs and outline implementation considerations.

Main Methods:

Literature review focusing on diagnostic stewardship interventions.
Analysis of the interplay between diagnostic and antimicrobial stewardship strategies.
Discussion of evidence supporting the benefits of diagnostic stewardship.

Main Results:

Diagnostic stewardship interventions can significantly improve antimicrobial use.
Integrated diagnostic and antimicrobial stewardship enhances patient outcomes.
Active engagement of antimicrobial stewardship programs is vital for successful diagnostic stewardship.

Conclusions:

Diagnostic stewardship is essential for effective antimicrobial stewardship.
Antimicrobial stewardship programs should spearhead the development of diagnostic stewardship interventions.
Successful implementation requires collaboration and strategic planning within healthcare institutions.