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Updated: Aug 8, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Chronic Mesenteric Ischemia in a Patient With Limited Systemic Sclerosis
Ashley Barasa1, Geoffrey Bader2
1Internal Medicine, San Antonio Military Medical Center, San Antonio, USA.
Abstract:
Chronic mesenteric ischemia typically develops secondary to the development of atherosclerosis within mesenteric vessels leading to the insufficient blood supply. While autoimmune conditions are an established independent risk factor for developing atherosclerotic plaques, the association between scleroderma and chronic mesenteric ischemia has been less studied. We present a case of a 64-year-old female with limited systemic sclerosis and atherosclerotic cardiovascular disease who presented to the Gastroenterology Clinic with progressive abdominal pain who was subsequently diagnosed with chronic mesenteric ischemia secondary to superior mesenteric artery stenosis and successfully treated with endovascular stenting.
Insights
Scleroderma, an autoimmune condition, is linked to atherosclerosis. This case study highlights chronic mesenteric ischemia in a scleroderma patient, successfully treated with endovascular stenting, improving blood flow.
Area of Science:
- Cardiovascular Medicine
- Gastroenterology
- Rheumatology
Background:
- Atherosclerosis in mesenteric vessels commonly causes chronic mesenteric ischemia.
- Autoimmune conditions are known risk factors for atherosclerosis.
- The link between scleroderma and chronic mesenteric ischemia is not well-established.
Observation:
- A 64-year-old female with limited systemic sclerosis and cardiovascular disease presented with progressive abdominal pain.
- The patient was diagnosed with chronic mesenteric ischemia due to superior mesenteric artery stenosis.
Findings:
- Endovascular stenting was successfully used to treat the superior mesenteric artery stenosis.
- This intervention restored adequate blood supply, resolving the patient's symptoms.
Implications:
- This case underscores the importance of considering chronic mesenteric ischemia in scleroderma patients with abdominal pain.
- It highlights endovascular stenting as a viable treatment option.
- Further research into the association between scleroderma and mesenteric vascular disease is warranted.
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