Related Experiment Video
Updated: Aug 8, 2025
06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
1.3K
Sarcoidosis presenting as optic neuritis with vision loss
Ryosuke Kataoka1, Yoshiro Kai1, Hiroya Ohara2
1Department of Respiratory Medicine Minami-Nara General Medical Center Nara Japan.
Respirology Case Reports
|February 27, 2023
Summary
Neurosarcoidosis, a rare complication of sarcoidosis, can cause optic neuritis and vision loss. Early diagnosis and treatment are crucial for potential vision recovery.
Area of Science:
- Neurology
- Ophthalmology
- Rheumatology
Background:
- Sarcoidosis is a multisystem inflammatory disease.
- Neurosarcoidosis is a rare but serious complication.
- Optic neuritis is an unusual presentation of neurosarcoidosis.
Observation:
- A 51-year-old man presented with vision loss in his right eye.
- MRI revealed optic nerve enlargement; CT showed lymphadenopathy and skin nodules.
- Biopsy confirmed noncaseating granulomas, consistent with sarcoidosis.
Findings:
- Elevated serum angiotensin-converting enzyme (ACE) levels.
- Diagnosis of neurosarcoidosis with optic neuritis.
- Partial vision improvement after high-dose corticosteroids.
Implications:
- Sarcoidosis should be considered in the differential diagnosis of optic neuritis.
- Prompt diagnosis and treatment can lead to improved visual outcomes.
- Highlights the importance of a multidisciplinary approach in managing complex cases.
Related Concept Videos
01:25Glaucoma: Overview
668
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
668
01:27Open Angle Glaucoma: Treatment
512
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
512
01:28Angle Closure Glaucoma: Treatment
602
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
602
01:22Photoreceptors and Visual Pathways
6.2K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.2K