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Atrophic dermatofibrosarcoma protuberans: Two case reports and literature review
Yiting Li1, Zile Chen1, Shu Nie1
1Department of Dermatology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in Oncology
|February 27, 2023
Summary
Atrophic dermatofibrosarcoma protuberans, a rare variant of a slow-growing skin cancer, often presents as subtle plaques. Early identification is crucial for better patient outcomes.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin cancer.
- DFSP has a high recurrence rate but low metastatic potential.
- Atrophic DFSP is an uncommon variant often misdiagnosed due to its subtle presentation.
Observation:
- This report details two cases of atrophic DFSP, one with pigmentation.
- The lesions presented as atrophic plaques, easily overlooked.
- Literature review of similar cases was conducted.
Findings:
- Atrophic DFSP can mimic benign skin conditions.
- Pigmentation can be a feature of this variant.
- Early recognition is key to differentiating it from benign lesions.
Implications:
- Timely diagnosis of atrophic DFSP improves patient prognosis.
- Awareness of this variant aids clinicians in avoiding misdiagnosis.
- Further understanding of DFSP variants is essential for effective management.
