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Updated: Aug 8, 2025

Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Multiple rare organisms causing ventriculoperitoneal shunt infection and brain abscess
Omar M Shihadeh1, Hayel Amin1, Firas Hammadi1
1Hamad Medical Corporation, Hamad General Hospital, Neurosurgery Department. E-mail: oshihadeh@hamad.qa ORCID ID: 0000-0001-8505-5147.
Abstract:
Ventriculoperitoneal shunts (VPS) are inserted to treat issues with CSF flow dynamics, such as obstructions causing CSF build up which raises the intracranial pressure. A major complication of this procedure is VPS infections. Vast majority of VPS infections are monomicrobial and may occur in the first two years of insertion due to contiguous or hematogenous spread. Here, we report a rare case of polymicrobial VPS infection with 5 pathogens. One of these organisms (Citrobacter werkmanii) has been reported as a cause of meningitis for the first time in this report. The other organism (Enterococcus casseliflavus) has been reported as a cause only one other time. Hence, we recommend considering these newly emerging organisms when dealing with meningitis.
Insights
Ventriculoperitoneal shunts (VPS) can become infected, often by a single microbe. This case details a rare polymicrobial VPS infection involving five pathogens, including two rarely reported in meningitis cases.
Area of Science:
- Neuroscience
- Infectious Diseases
- Medical Microbiology
Background:
- Ventriculoperitoneal shunts (VPS) manage cerebrospinal fluid (CSF) dynamics and intracranial pressure.
- VPS infections are a significant complication, typically monomicrobial and occurring within two years of placement.
- Infections can arise from contiguous spread or the bloodstream.
Observation:
- This report presents an exceptionally rare case of a polymicrobial VPS infection.
- The infection involved five distinct microbial pathogens.
- Two specific organisms, *Citrobacter werkmanii* and *Enterococcus casseliflavus*, were identified.
Findings:
- *Citrobacter werkmanii* is identified as a causative agent of meningitis for the first time.
- *Enterococcus casseliflavus* is reported as a cause of meningitis for only the second time.
- The polymicrobial nature of this VPS infection is highly unusual.
Implications:
- This case highlights the emergence of less common pathogens in VPS infections.
- Clinicians should consider a broader range of organisms, including *C. werkmanii* and *E. casseliflavus*, when diagnosing meningitis.
- Further research into emerging pathogens causing VPS infections is warranted.
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