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Updated: Aug 8, 2025
Biofunctionalization of Magnetic Nanomaterials
Published on: July 16, 2020
Enhanced Peroxidase-Like and Antibacterial Activity of Ir-CoatedPd-Pt Nanodendrites as Nanozyme
Jingfang Song1, Jian He2, Lin Yang2
1The Second Affiliated Hospital, Department of Pediatrics, Institute of Pathogenic Biology, Hengyang Medical School, University of South China and Hunan Provincial Key Laboratory for Special Pathogens Prevention and Control, Hengyang, Hunan 421001, China.
Abstract:
To inhibit the growth of bacteria, the DA-PPI nanozyme with enhanced peroxidase-like activity was synthesized. The DA-PPI nanozyme was obtained by depositing high-affinity element iridium (Ir) on the surface of Pd-Pt dendritic structures. The morphology and composition of DA-PPI nanozyme were characterized using SEM, TEM, and XPS. The kinetic results showed that the DA-PPI nanozyme possessed a higher peroxidase-like activity than that of Pd-Pt dendritic structures. The PL, ESR, and DFT were employed to explain the high peroxidase activity. As a proof of concept, the DA-PPI nanozyme could effectively inhibit E. coli (G-) and S. aureus (G+) due to its high peroxidase-like activity. The study provides a new idea for the design of high active nanozymes and their application in the field of antibacterial.
