Related Experiment Video
Updated: Aug 8, 2025

04:17
Author Spotlight: Development and Evaluation of a Standardized Rat Model for Calvarial Suture-Bony Composite Defects
Published on: May 10, 2024
724
Secondary Corrections for Single-Suture Craniosynostosis: Perioperative Outcomes and Predisposing Factors
Aditi Kanth1, Kanlaya Ditthakasem2, Morley Herbert2
1From the Robert Wood Johnson Hospital.
Plastic and Reconstructive Surgery
|February 27, 2023
Summary
Secondary craniosynostosis remodeling procedures do not appear to have higher complication rates. However, younger age at primary correction and strip craniectomies may increase the likelihood of needing a subsequent operation.
Area of Science:
- Craniofacial surgery
- Pediatric neurosurgery
- Plastic surgery
Background:
- Many single-suture craniosynostosis corrections necessitate secondary remodeling procedures.
- The necessity for secondary procedures raises concerns about potentially higher complication rates and predisposing factors.
Purpose of the Study:
- To determine if secondary craniosynostosis remodeling procedures carry higher complication rates compared to primary corrections.
- To explore potential predisposing factors associated with the need for secondary remodeling procedures.
Main Methods:
- Retrospective chart review of patients undergoing primary and secondary craniosynostosis corrections.
- Data collected from a single center between 2010 and 2020.
- Analysis included complication rates, blood transfusion rates, length of stay, and predisposing factors.
Main Results:
- Of 491 single-suture corrections, 111 were secondary procedures (89.2% initially treated elsewhere).
- Surgical infection rates and median hospital length of stays were similar between primary and secondary groups.
- Younger age at primary correction (median 6 months vs. 12 months) was significantly associated with needing a second procedure, with a 40% odds reduction for each month increase in age.
Conclusions:
- This single-center review did not identify a higher risk profile for complications in secondary craniosynostosis remodeling procedures.
- Performing primary corrections at a younger age appears to be a significant factor associated with the need for subsequent secondary correction.
- Strip craniectomies may also be associated with a higher likelihood of requiring a secondary procedure.

