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Enhancer Coamplification and Hijacking Promote Oncogene Expression in Liposarcoma.

Tingting Liu1, Juan Wang1, Hongbo Yang1

  • 1Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine Northwestern University, Chicago, Illinois.

Cancer Research
|February 27, 2023
PubMed
Summary

This study reveals how gene enhancers and 3D genome structure drive liposarcoma. It identifies key enhancer-oncogene coamplification and hijacking events in cancer, improving understanding of oncogene regulation.

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