Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Analysis of the Influence of Sex in 507 Patients With Moderate-to-Severe Atopic Dermatitis: Spanish Atopic Dermatitis Registry (BIOBADATOP).

Actas dermo-sifiliograficas·2026
Same author

Health Care Resource Utilization in Patients With Atopic Dermatitis According to Treatment Response: Evidence From the BIOBADATOP Registry.

Actas dermo-sifiliograficas·2026
Same author

Characteristics, Treatment, and Safety Profile of Patients With Atopic Dermatitis According to Eligibility for Randomized Clinical Trials: An Analysis From the Spanish Atopic Dermatitis Registry (BIOBADATOP).

Actas dermo-sifiliograficas·2025
Same author

[Translated article] Should Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde (Lyral®) Still be Part of the Baseline Series?

Actas dermo-sifiliograficas·2025
Same author

Should Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde (Lyral®) still be part of the Baseline Series?

Actas dermo-sifiliograficas·2025
Same author

Hidden Dangers of Oral Contrast Media: Delayed Hypersensitivity to Sodium Amidotrizoate and Meglumine Amidotrizoate (Gastrografin).

Journal of investigational allergology & clinical immunology·2025

Related Experiment Video

Updated: Aug 8, 2025

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

2.8K

[Translated article] Haptens, Proteins, and Atopic Dermatitis.

V Amat-Samaranch1, J F Silvestre Salvador2

  • 1Servicio de Dermatología, Hospital Clínic de Barcelona, Barcelona, Spain.

Actas Dermo-Sifiliograficas
|February 27, 2023
PubMed
Summary

Atopic dermatitis patients often experience flare-ups due to allergic contact and protein contact dermatitis. Skin testing is recommended to identify triggers and manage exacerbations effectively.

Keywords:
Atopic dermatitisContact dermatitisDermatitis atópicaDermatitis de contactoDupilumabEpicutáneasPatch testPrick test

More Related Videos

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation
02:36

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation

Published on: March 8, 2024

1.1K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

24.6K

Related Experiment Videos

Last Updated: Aug 8, 2025

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis
08:25

Contact Hypersensitivity as a Murine Model of Allergic Contact Dermatitis

Published on: September 26, 2022

2.8K
Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation
02:36

Author Spotlight: Effective Reuse of Polycarbonate Tubes for Extracellular Vesicle Isolation

Published on: March 8, 2024

1.1K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

24.6K

Area of Science:

  • Dermatology
  • Immunology

Background:

  • Atopic dermatitis is a chronic, multifactorial inflammatory skin condition.
  • Allergic contact dermatitis and protein contact dermatitis can trigger exacerbations in atopic dermatitis patients.
  • Atopic inflammation compromises the skin barrier, increasing susceptibility to allergens.

Purpose of the Study:

  • To review the association between atopic dermatitis and allergic/protein contact dermatitis.
  • To discuss diagnostic approaches and management strategies for these conditions in atopic individuals.
  • To explore the potential role of Dupilumab in managing allergic contact dermatitis within atopic dermatitis.

Main Methods:

  • Literature review of studies on atopic dermatitis, allergic contact dermatitis, and protein contact dermatitis.
  • Analysis of diagnostic recommendations, including skin testing (patch and prick tests).
  • Discussion of therapeutic considerations, including allergen avoidance and targeted treatments like Dupilumab.

Main Results:

  • Skin barrier disruption in atopic dermatitis increases the likelihood of associated allergic conditions.
  • Skin tests are crucial for identifying allergens in atopic dermatitis patients.
  • Dupilumab's efficacy in allergic contact dermatitis depends on the T-cell response (T helper 2 vs. T helper 1), requiring further investigation.

Conclusions:

  • Allergic contact and protein contact dermatitis are significant contributors to atopic dermatitis exacerbations.
  • Prompt diagnosis via skin testing and subsequent allergen avoidance are key management strategies.
  • Further research is needed to clarify Dupilumab's role in specific subtypes of allergic contact dermatitis associated with atopic dermatitis.