Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cross-reactivity00:42

Cross-reactivity

31.4K
Overview
31.4K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

103
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
103
Vaccinations01:51

Vaccinations

45.1K
Overview
45.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering extracellular vesicle biogenesis for therapeutic gene delivery: emerging genetic programming strategies and translational prospects.

Molecular biology reports·2026
Same author

3D-printed lab-on-chip platforms for the detection of neurodegenerative diseases: opportunities and challenges.

Journal of materials chemistry. B·2026
Same author

Role of gut microbiota in cancer modulation: molecular mechanisms and emerging therapeutic strategies.

Infectious agents and cancer·2026
Same author

Heat Exposure and Health Outcomes in Construction Workers: A Systematic Review and Meta-Analysis.

Environmental health insights·2026
Same author

Active nanorobotic systems for blood-based detection of cancer biomarkers: from passive nanosensors to dynamic liquid biopsy platforms.

Biomedical microdevices·2026
Same author

Association Between Family Dysfunction and Risk for Eating Disorders in Adolescents.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Aug 8, 2025

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
10:11

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes

Published on: September 27, 2014

36.4K

Ebola Virus Disease Vaccines: Development, Current Perspectives & Challenges.

Sumira Malik1, Shristi Kishore1, Sagnik Nag2

  • 1Amity Institute of Biotechnology, Amity University Jharkhand, Ranchi 834001, Jharkhand, India.

Vaccines
|February 28, 2023
PubMed
Summary

Developing effective Ebola vaccines requires systematic protocols and addressing challenges in immunogenicity, rapid response, and long-term protection. Manufacturing and distribution also need careful planning for future outbreaks.

Keywords:
Ebola outbreakEbola vaccinesEbola virus disease (EVD)challenges

More Related Videos

Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.2K
Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle VLP-Based Vaccines Using a Capture Assay
05:15

Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle VLP-Based Vaccines Using a Capture Assay

Published on: February 10, 2022

3.7K

Related Experiment Videos

Last Updated: Aug 8, 2025

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
10:11

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes

Published on: September 27, 2014

36.4K
Remote Laboratory Management: Respiratory Virus Diagnostics
14:56

Remote Laboratory Management: Respiratory Virus Diagnostics

Published on: April 6, 2019

33.2K
Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle VLP-Based Vaccines Using a Capture Assay
05:15

Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle VLP-Based Vaccines Using a Capture Assay

Published on: February 10, 2022

3.7K

Area of Science:

  • Virology and Immunology
  • Vaccine Development
  • Public Health

Background:

  • Recent Ebola virus disease (EVD) outbreaks highlight limitations of existing vaccines.
  • There is an urgent need for systematic protocols for pre-outbreak Ebola vaccine production.
  • Current vaccine development faces challenges in achieving desired immune responses and longevity.

Purpose of the Study:

  • To review the current state of Ebola vaccine development.
  • To discuss the challenges and limitations in creating effective EVD vaccines.
  • To explore future perspectives and strategies for combating emerging Ebola outbreaks.

Main Methods:

  • Review of existing literature on Ebola vaccine development.
  • Analysis of various vaccine platforms including virus-like particle, DNA, and recombinant vaccines.
  • Examination of challenges in immunogenicity, cross-protection, and vaccine manufacturing.

Main Results:

  • Several vaccine types are in preclinical and clinical trials.
  • Key challenges include selecting immunogenic, rapidly responsive, and cross-protective candidates.
  • Post-authorization processes like licensing and surveillance are critical for efficacy.

Conclusions:

  • Systematic protocols for Ebola vaccine development are crucial.
  • Overcoming challenges in vaccine design and manufacturing is essential for future preparedness.
  • Continued research and strategic planning are necessary to combat emerging Ebola threats.