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Nanomedicine as a Potential Tool against Monkeypox.
Nura Adam Mohamed1, Luisa Zupin2, Sarah Ismail Mazi3
1Biomedical Research Center (BRC), Qatar University, Doha P.O. Box 2713, Qatar.
Vaccines
|February 28, 2023
Summary
Monkeypox, a viral zoonosis endemic to Africa, is now a global epidemic with no proven treatment. This review explores nanomedicine strategies to combat monkeypox and prevent future pandemics.
Area of Science:
- Virology
- Nanomedicine
- Public Health
Background:
- Human monkeypox (MPXV) is a viral zoonosis endemic to Central and Western Africa, recognized as the most significant orthopoxvirus in humans post-smallpox eradication.
- Recent global outbreaks indicate a shift from a rare, self-limiting disease to a potential epidemic, highlighting the urgent need for effective interventions.
- The lack of proven treatments and ongoing vaccine development questions necessitate exploring novel preventative strategies, drawing parallels with the COVID-19 pandemic response.
Purpose of the Study:
- To review existing nanomedicine approaches for combating human monkeypox.
- To identify research gaps and suggest future directions for nanomedicine-based strategies against MPXV.
- To contribute to developing preventative measures against emerging viral threats and potential pandemics.
Main Methods:
- Systematic literature review of reported nanomedicine applications for monkeypox.
- Analysis of current data on nanotechnology and nanomaterial use in medical research relevant to MPXV.
- Identification of trends and limitations in existing nanomedicine research for viral infections.
Main Results:
- Data on nanomedicine interventions for monkeypox is currently limited, dispersed, and often incomplete.
- Nanotechnology offers potential for developing novel preventative strategies against MPXV, leveraging advancements in nanomaterials for medical applications.
- The review identifies a critical need for further research to establish effective nanomedicine-based countermeasures.
Conclusions:
- Nanomedicine presents a promising avenue for developing preventative strategies against the escalating monkeypox epidemic.
- Further investigation into nanomedicine approaches is crucial to mitigate the current MPXV outbreak and prepare for future viral pandemics.
- A proactive, nanomedicine-based approach is warranted, especially considering the lessons learned from the COVID-19 pandemic.
