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Percutaneous thrombectomy of upper extremity and thoracic central veins using Inari ClotTriever System: Experience in
Ashley M Sweeney1, Mina S Makary1, Colvin Greenberg2
1Division of Vascular and Interventional Radiology, Department of Radiology, The Ohio State University Wexner Medical Center, Columbus, OH.
Insights
Percutaneous thrombectomy using the ClotTriever system effectively treated deep venous occlusive disease in upper extremity and thoracic veins. This minimally invasive procedure achieved excellent technical and clinical success, resolving patient symptoms without major adverse events.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiovascular Medicine
Background:
- Deep venous occlusive disease in the upper extremity and thoracic central veins can cause significant morbidity.
- Malignancy, infection, and benign etiologies can lead to thrombus formation in these critical venous structures.
- Traditional treatments may have limitations, necessitating advanced minimally invasive options.
Purpose of the Study:
- To evaluate the technical and clinical outcomes of percutaneous thrombectomy using the ClotTriever system for deep venous occlusive disease in the upper extremity and thorax.
- To assess the feasibility and safety of the ClotTriever system in this patient population.
Main Methods:
- A retrospective review of 14 patients who underwent thrombectomy with the ClotTriever system between October 2020 and January 2022.
- Data collected included technical success, adverse events, imaging follow-up, and clinical outcomes.
- Patients presented with symptomatic venous occlusive disease due to malignancy, infection, or benign causes.
Main Results:
- Successful thrombectomy was achieved in all 14 patients.
- The primary indications for treatment included malignancy-related DVT (64.3%), infected thrombi (14.3%), and benign etiologies (21.4%).
- All patients experienced symptom resolution, with 50% requiring additional venous stent reconstruction; no major adverse events were reported.
Conclusions:
- Percutaneous thrombectomy with the ClotTriever system is a feasible and effective treatment for symptomatic deep venous occlusive disease in the upper extremity and thoracic veins.
- The procedure demonstrates excellent technical and clinical success rates with a favorable safety profile.
- The ClotTriever system offers a valuable minimally invasive therapeutic option for complex venous occlusions.
Objective:
In the present report, we have described the technical and clinical outcomes of percutaneous thrombectomy in the deep veins of the upper extremity and thorax using the ClotTriever system (Inari Medical, Irvine, CA).
Methods:
Fourteen patients with symptomatic deep venous occlusive disease in the upper extremity deep veins and thoracic central veins who had undergone thrombectomy using the ClotTriever system between October 2020 and January 2022 were reviewed. The technical results, adverse events, imaging follow-up data, and clinical outcomes were recorded.
Results:
Fourteen patients (seven men and seven women; mean age, 53.6 ± 13.3 years) constituted the study cohort. Of the 14 patients, 9 (64.3%) had had DVT due to intravascular invasion or external compression from known malignancy, 2 (14.3%) had had infected thrombi and/or vegetation due to Staphylococcus aureus refractory to intravenous antibiotic therapy, and 3 (21.4%) had had a benign etiology for thrombus formation. The presenting symptoms included upper extremity and/or facial swelling (n = 14), upper extremity pain (n = 6), fever (n = 2), and dyspnea (n = 1). Thrombectomy with the ClotTriever system was successfully completed in all 14 patients. Seven patients (50.0%) had required additional venous stent reconstruction after thrombectomy to address the underlying stenosis. No major adverse events were noted. All the patients had experienced resolution of the presenting symptoms.
Conclusions:
For the management of symptomatic deep venous occlusive disease of the upper extremity deep veins and thoracic central veins, thrombectomy using the ClotTriever system was feasible with excellent technical and clinical success.
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