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Updated: Aug 8, 2025

Author Spotlight: Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model
Published on: March 31, 2023
Clinical study of complications of a peripherally inserted central catheter in cancer patients
André Luis Victor Bonfim1, Germana Alves de Brito1, Aline Lourenço Baptista1
1Department of Nephrology, A.C. Camargo Cancer Center, São Paulo, Brazil.
Aim:
To evaluate complications after PICC use in cancer patients.
Design:
This was a clinical and retrospective study in which the risk factors and complications of PICC use were evaluated.
Methods:
This study was carried out in the patient, emergency room, and intensive care units through the evaluation of electronic medical records. To assess the association between qualitative variables, the chi-squared test or Fisher's exact test was used, and to compare the reason for withdrawal, the Kruskal-Wallis test was applied.
Results:
A total of 359 patients (53.5% men) with 43.1 ± 14 years who had a PICC (88% with solid tumours) were evaluated. The most common complications were mechanical complications (61.2%), infection (38%), and thrombosis (57.1%). Patients with double-lumen catheters experienced thrombosis (85.7%). This study demonstrated the effectiveness of PICC and that patients with haematological cancer are more prone to multiple PICC passages and more mechanical complications and infections.
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