Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

3.5K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Small Femoral Nails and the Development of a Nonunion: A Case-Control Study.

Orthopedics·2026
Same author

Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol.

BMJ open·2026
Same author

Adverse Mental Health Outcomes after Modern External Ring Fixation Versus Internal Fixation for Severe Open Tibia Fractures: A Secondary Analysis of the FIXIT Study.

Journal of orthopaedic trauma·2026
Same author

Infection Rate by Gustilo-Anderson Classification in Open Tibial Shaft Fractures Treated with an Intramedullary Nail - A Meta-Analysis.

Journal of orthopaedic trauma·2026
Same author

Do antibiotic bead pouches prevent infections and other complications in patients with Gustilo-Anderson Type III open lower extremity fractures?

Injury·2026
Same author

Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures: The TOBRA Randomized Clinical Trial.

JAMA·2026

Related Experiment Video

Updated: Aug 8, 2025

Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
15:11

Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling

Published on: January 5, 2015

63.8K

Small-Fragment Plate Fixation of Humeral Shaft Fractures.

Christopher G Langhammer, Giuliana Rotunno, Christina Sebastian

    Orthopedics
    |February 28, 2023
    PubMed
    Summary

    Small-fragment (3.5 mm) plates are a safe alternative for humeral shaft fracture fixation, showing similar nonunion and radial nerve palsy rates compared to large-fragment (4.5 mm) plates. Postoperative weight-bearing status did not impact outcomes with either plate size.

    More Related Videos

    Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies
    05:45

    Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies

    Published on: April 12, 2024

    641
    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
    06:38

    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

    Published on: October 12, 2016

    10.1K

    Related Experiment Videos

    Last Updated: Aug 8, 2025

    Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling
    15:11

    Surgical Fixation of Sternal Fractures: Preoperative Planning and a Safe Surgical Technique Using Locked Titanium Plates and Depth Limited Drilling

    Published on: January 5, 2015

    63.8K
    Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies
    05:45

    Author Spotlight: Exploring Regeneration in Axolotls Through Insights in Cellular and Molecular Mechanisms, Bone Healing, and Implications for Human Therapies

    Published on: April 12, 2024

    641
    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
    06:38

    Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

    Published on: October 12, 2016

    10.1K

    Area of Science:

    • Orthopedic Surgery
    • Trauma Management
    • Biomechanical Engineering

    Background:

    • Humeral shaft fracture fixation commonly uses large-fragment (4.5 mm) plates for immediate weight-bearing.
    • Small-fragment (3.5 mm) plates offer theoretical advantages for treating these fractures.

    Purpose of the Study:

    • To compare nonunion and radial nerve palsy (RNP) rates between 3.5-mm and 4.5-mm plate fixation for humeral shaft fractures.
    • To evaluate the influence of postoperative weight-bearing status on fracture healing and RNP.

    Main Methods:

    • Retrospective cohort study of 241 humeral shaft fractures in 236 patients.
    • Analysis of open reduction and internal fixation using either 3.5-mm or 4.5-mm plates.
    • Assessment of nonunion and RNP rates, with subgroup analysis for weight-bearing status.

    Main Results:

    • Nonunion rates were 7% for both 3.5-mm and 4.5-mm plates.
    • RNP rates were 10% for 3.5-mm plates and 15% for 4.5-mm plates.
    • No statistically significant difference in nonunion or RNP rates was found based on plate size or postoperative weight-bearing status.

    Conclusions:

    • Small-fragment (3.5 mm) plate fixation is a safe and effective alternative to large-fragment (4.5 mm) plates for humeral shaft fractures.
    • Plate size does not significantly affect union or RNP rates.
    • Postoperative weight-bearing status does not influence outcomes in either group.