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Prednisolone prescribing practices for dogs in Australia
Bonnie Purcell1, Anke Wiethoelter1, Julien Dandrieux1,2
1Melbourne Veterinary School, Faculty of Science, The University of Melbourne, Parkville, Victoria, Australia.
Plos One
|February 28, 2023
Summary
Veterinary prescribing practices for prednisolone in dogs show it
Area of Science:
- Veterinary Medicine
- Pharmacology
- Canine Health
Background:
- Prednisolone is a common medication for dogs.
- There is limited data on how veterinarians prescribe it.
- Understanding current practices is crucial for optimizing canine treatment.
Purpose of the Study:
- To describe prednisolone prescribing patterns in Australian dogs.
- To identify factors influencing prescribed doses.
- To compare dosing between large and small breeds for similar conditions.
Main Methods:
- Utilized the VetCompass Australia database (July 2016-July 2018).
- Randomly selected 2,000 dogs prescribed prednisolone.
- Analyzed demographic data, doses, and indications using multivariable linear regression.
Main Results:
- Median age was 73 months, median weight 17 kg.
- Most dogs (58%) received anti-inflammatory doses (0.3-1 mg/kg/day).
- Higher body weight correlated with lower mg/kg doses but higher mg/m2 doses.
Conclusions:
- Prednisolone is primarily used for anti-inflammatory purposes in dogs.
- Some dogs received higher immunosuppressive doses than indicated.
- Veterinarians appear to adjust prednisolone doses based on dog body weight.
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