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Endoscopic image-guided laser treatment system based on fiber bundle laser steering
Yuto Miyoshi1, Takahiro Nishimura2, Yu Shimojo3
1Graduate School of Engineering, Osaka University, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan. miyoshi-a-y@mb.see.eng.osaka-u.ac.jp.
Scientific Reports
|February 28, 2023
Summary
A new endoscopic laser system uses a single fiber bundle for imaging and laser steering, enabling precise treatment of micro-lesions in narrow organs like blood vessels and the lungs.
Area of Science:
- Medical Engineering
- Minimally Invasive Surgery
- Laser Technology
Background:
- Conventional endoscopic laser systems face limitations in narrow anatomical spaces due to separate optical paths for imaging and laser steering.
- Accessing and treating micro-lesions within confined organs requires advanced miniaturized instrumentation.
Purpose of the Study:
- To develop and evaluate a novel, miniaturized endoscopic image-guided laser treatment system capable of accessing narrow organs.
- To enable simultaneous endoscopic imaging and laser steering through a single fiber bundle for precise lesion targeting.
Main Methods:
- A novel endoscopic system with a thin tip was designed, integrating imaging and laser steering via a single fiber bundle.
- System functionality was demonstrated in an artificial vascular model, assessing insertion and operation in narrow spaces.
- Laser steering accuracy and repeatability were quantified using root-mean-square error and dispersion radius measurements.
- Strategies to mitigate fiber bundle crosstalk and control laser input were implemented.
- The system's ability to control photothermal effects, vaporization, and coagulation in biological tissue (chicken liver) was investigated.
Main Results:
- The system successfully demonstrated insertion and operation within a narrow artificial vascular model.
- Accurate laser irradiation was achieved with a root-mean-square error of 28 µm.
- High static repeatability was observed, with laser irradiation positions controlled within a 12 µm radius.
- Fiber bundle crosstalk was minimized by optimizing the laser input diameter.
- The laser steering trajectory effectively controlled photothermal effects, vaporization, and coagulation in chicken liver tissue.
Conclusions:
- This novel endoscopic system facilitates minimally invasive laser treatment within narrow organs.
- The integrated approach using a single fiber bundle enhances precision and lesion selectivity.
- The system shows significant potential for applications in treating conditions within the peripheral lung and coronary arteries.
