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Generation of Fluorescent Protein Fusions in Candida Species
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Congenital Cutaneous Candidiasis in Preterm Infants
Chelsea Shope1, Alexandra Ritter1, Samantha Karlin2
1College of Medicine, Medical University of South Carolina, Charleston, SC.
Neoreviews
|March 1, 2023
Summary
Congenital cutaneous candidiasis (CCC) is a rare neonatal rash. Early diagnosis and intravenous fluconazole treatment are crucial for preventing disease progression in affected infants.
Area of Science:
- Neonatal dermatology
- Infectious diseases
Background:
- Congenital cutaneous candidiasis (CCC) is a rare fungal infection affecting newborns.
- Typically observed in premature and low birthweight infants, CCC presents with diverse skin manifestations.
Approach:
- This review synthesizes current knowledge on CCC.
- Key areas covered include epidemiology, pathogenesis, clinical presentation, diagnostic methods, and management strategies.
Key Points:
- CCC diagnosis can be challenging due to varied clinical presentations, including desquamation, maculopapular lesions, pustules, vesicles, or bullae.
- Prompt identification is critical for effective intervention.
Conclusions:
- Early treatment with intravenous fluconazole is essential for managing CCC and preventing complications.
- This review provides a comprehensive overview for clinicians managing this rare neonatal condition.
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