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Updated: Aug 8, 2025

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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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The Support, Educate, Empower personalized glaucoma coaching trial design.
Paula Anne Newman-Casey1,2, Ken Resnicow2,3, Suzanne Winter1
1Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI, USA.
Clinical Trials (London, England)
|March 1, 2023
Summary
Personalized coaching significantly improved glaucoma medication adherence in a randomized trial. This intervention addresses adherence barriers, offering a scalable solution for better patient outcomes in glaucoma management.
Area of Science:
- Ophthalmology
- Public Health
- Behavioral Science
Background:
- Glaucoma affects 3 million Americans, often asymptomatic until advanced stages.
- Medication adherence is crucial but challenging, with over half of patients not taking prescribed drugs regularly.
- Late-stage diagnosis complicates treatment and increases the risk of irreversible peripheral vision loss.
Purpose of the Study:
- To enhance glaucoma medication adherence in patients with poor self-reported adherence.
- To evaluate the effectiveness of the Support, Educate, Empower personalized coaching program.
Main Methods:
- A two-site randomized controlled trial with 230 participants.
- Intervention group received personalized coaching and reminders; control group received usual care and general education.
- Primary outcome: proportion of prescribed doses taken on schedule over 6 months; secondary outcome: glaucoma-related distress.
Main Results:
- The study aims to determine if personalized coaching improves medication adherence compared to usual care.
- It will also assess the impact on glaucoma-related distress and intraocular pressure.
Conclusions:
- The personalized, motivational interviewing-based coaching program is designed to be comprehensive and address diverse adherence barriers.
- A web-based application ensures replicability and scalability for integration into clinical practice.
- This trial may inform future healthcare policy regarding reimbursement for such self-management support interventions.
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