Elimination of Enterococcus faecalis from root canal system using laser-activated nanoparticles: a systematic review

Elimination of Enterococcus faecalis is vital during root canal treatment. Owing to their antimicrobial properties, laser-activated nanoparticles (NPs) have been used in root canal irrigation in the recent past. The aim of this review is to conduct a qualitative analysis of the published data evaluating the antibacterial efficacy of laser-activated nanoparticles in the elimination of E. faecalis from the root canal system. Considering all the papers published till August 2022, a search of the databases PubMed, SCOPUS, and EBSCOhost was conducted. All the articles that were published in English were included. The review process was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. The risk of bias was assessed after the extraction of the data. After screening the distinguished 51 studies according to the inclusion criteria, five in vitro studies were included for the systematic review. A systematic review of the selected studies showed a positive impact on E. faecalis load reduction following irrigation with nanoparticles irradiated using lasers. Laser-activated nanoparticles have shown superior antibacterial efficacy compared to conventional irrigation techniques and may be used as an alternative for root canal disinfection.