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Transcatheter Intervention for Coarctation of the Aorta: A Nordic Population-Based Registry With Long-Term Follow-Up

Peter Eriksson1, Jaana Pihkala2, Annette S Jensen3

  • 1University of Gothenburg, Institute of Medicine, Sahlgrenska Academy, Gothenburg, Sweden.

JACC. Cardiovascular Interventions
|March 1, 2023
PubMed

Insights

Transcatheter intervention for coarctation of the aorta (CoA) is a safe procedure with low complication rates. However, long-term monitoring is essential as many patients remain hypertensive post-intervention.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Congenital Heart Disease

Background:

  • Coarctation of the aorta (CoA) is a common congenital heart defect causing significant morbidity and mortality.
  • Transcatheter intervention (TCI) has emerged as a viable alternative to surgery for CoA.
  • This study analyzes TCI outcomes for CoA over a 16-year period.

Purpose of the Study:

  • To evaluate the safety and efficacy of transcatheter interventions for coarctation of the aorta.
  • To assess procedural success rates and complication profiles of TCI for CoA.
  • To determine the long-term impact of TCI on hypertension and the need for further interventions.

Main Methods:

  • Retrospective analysis of all TCIs for CoA performed between 2000 and 2016.
  • Data collected from 4 countries covering 25 million inhabitants.
  • Mean follow-up duration of 6.9 years for 542 patients undergoing 683 interventions.

Main Results:

  • Procedural success rate was 88%, with 3.5% complications at intervention and access sites.
  • No in-hospital mortality was observed.
  • TCI significantly reduced hypertension from 73% to 34%, but 8-9% required further aortic surgery during follow-up.

Conclusions:

  • Transcatheter intervention for CoA is associated with a low risk of complications.
  • Lifetime follow-up is recommended for patients undergoing TCI for CoA due to persistent hypertension and potential need for reintervention.
Abstract

Keywords:
catheter interventioncoarctation of Aortacongenital heart disease

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