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Updated: Aug 8, 2025

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[Research Progress in Pathogenesis of Hypertension in Acute Intermittent Porphyria]
Qing-Yang Li1, Yi Ren2, Jian-Hong Wang3
1The First Clinical Medical College,Shanxi Medical University,Taiyuan 030001,China.
Abstract:
Acute intermittent porphyria (AIP) has complicated clinical manifestations and is often accompanied by hypertension.AIP may cause hypertension through adrenergic effect,heme deficiency,inflammation,inappropriate secretion of antidiuretic hormone,toxicity of delta-aminolevulinic acid(ALA,aporphyrin precursor),and elevated serum glucose level.The prevention and treatment strategies for AIP accompanied with hypertension mainly include the controlling of porphyria attacks,application of antihypertensive drugs,lifestyle intervention,and management of latent AIP patients.
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